Opteon™ XP40 (R-449A) refrigerant

Opteon™ XP40 (R-449A) is a non-ozone depleting, low global warming potential (GWP) hydrofluoro-olefin (HFO) based refrigerant replacement for R-404A/R-507, R-407A/F, and R-22 for new equipment and retrofit of existing systems. Opteon™ XP40 has a GWP of 1397, which is a 65% reduction, and provides energy consumption 8-12% lower than R-404A/R-507. Compared to R-407A, Opteon™ XP40 offers improved performance, similar capacity and 34% lower GWP.


Commercial Refrigeration

  • Low- and medium-temperature commercial and industrial DX re- frigeration
  • Food service (e.g., condensing units)
  • Cold storage
  • Self-contained systems
  • Supermarkets
    - Centralized rack systems
    - Distributed systems
    - Walk-in coolers/freezers, prep rooms, etc.


  • Direct expansion
  • New equipment/retrofit of existing systems


  • Low GWP: 65% reduction compared to R-404A/R-507*
  • 8-12% more energy efficient than R-404A/R-507
  • Safe and nonflammable**
  • Approved by major equipment and component manufacturers
  • Alternative to R-407 series low- and medium-temperature re- frigerants
  • Compatible with existing equipment design/lubricants
  • Superior efficiency to CO2
  • Extensively field tested with no equipment/lubricant/seal changes***
  • Can be topped off after leaks

  * Assessment Report 4 (AR4)
 ** ASHRAE A1 Safety Classification
*** Superheat adjustment may be required


Opteon™ XP40 properties

What to Expect After a Retrofit

The data below was obtained from a display case/condensing unit converted to Opteon™ XP40 from R-404A with only adjustments to the TXV (1.5 turns closed) during low- and medium-temperature operation at two ambient conditions per ASHRAE Standard 72-2005.

Note that actual performance for a specific system depends on a number of factors, including equipment conditions and operating environment.

Opteon™ XP40: What to Expect After a Retrofit

Opteon™ XP40 In the News